Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.30 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12243175 | 1.00 | SMYD2 (0.32) | SMYD2PRMT5WDR77 | |
| SCHEMBL12243129 | 0.91 | SMYD2 (0.32) | SMYD2 | |
| SCHEMBL12243172 | 0.89 | PRMT5 (0.30) | PRMT5WDR77 | |
| SCHEMBL30090984 | 0.86 | TMPRSS2 (0.32) | SMYD2 | |
| SCHEMBL12243216 | 0.86 | TMPRSS2 (0.32) | SMYD2 | |
| SCHEMBL30931390 | 0.86 | TMPRSS2 (0.32) | SMYD2 | |
| SCHEMBL12243168 | 0.84 | PRMT5 (0.38) | PRMT5WDR77 | |
| SCHEMBL12243161 | 0.81 | PIK3CD (0.32) | PRMT5WDR77 | |
| SCHEMBL12243132 | 0.79 | — | — | |
| SCHEMBL30090997 | 0.79 | TMPRSS2 (0.42) | SMYD2PRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2480559-B1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF 1'-CYANO-CARBANUCLEOSIDE ANALOGS | GILEAD SCIENCES INC (US) | 2013-07-03 | — | — | EP | disclosed |