SCHEMBL1508501

SCHEMBL1508501

CCOC(CC(=O)O)c1ccc(OCc2ccc(C(F)(F)F)c(F)c2F)cc1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.70
PPARG P37231 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1508284 0.82 FFAR1 (0.84) FFAR1PPARG
SCHEMBL1508342 0.81 FFAR1 (0.71) FFAR1PPARG
SCHEMBL1508584 0.81 FFAR1 (0.64) FFAR1PPARG
SCHEMBL1508221 0.81 FFAR1 (0.64) FFAR1PPARG
SCHEMBL1508322 0.79 FFAR1 (0.80) FFAR1PPARG
SCHEMBL1508515 0.78 FFAR1 (1.00) FFAR1PPARG
SCHEMBL1508158 0.78 FFAR1 (1.00) FFAR1PPARG
SCHEMBL1508306 0.78 FFAR1 (1.00) FFAR1PPARG
SCHEMBL1508483 0.77 FFAR1 (0.77) FFAR1PPARG
SCHEMBL15936211 0.77 FFAR1 (0.43) FFAR1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2289868-B1 CARBOXYLIC ACID COMPOUND DAIICHI SANKYO CO LTD (JP) 2014-08-13 EP disclosed
EP-2289868-A1 CARBOXYLIC ACID COMPOUND Daiichi Sankyo Company, Limited (JP) 2011-03-02 EP disclosed