Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15085515 | 0.93 | BTK (0.62) | BTK | |
| SCHEMBL15085521 | 0.91 | BTK (0.63) | BTK | |
| SCHEMBL610224 | 0.86 | BTK (0.67) | BTK | |
| SCHEMBL611595 | 0.85 | BTK (0.65) | BTK | |
| SCHEMBL610704 | 0.84 | BTK (0.69) | BTK | |
| SCHEMBL610716 | 0.84 | BTK (0.66) | BTK | |
| SCHEMBL15085519 | 0.83 | BTK (0.68) | BTK | |
| SCHEMBL610670 | 0.82 | BTK (0.68) | BTK | |
| SCHEMBL610060 | 0.81 | BTK (0.67) | BTK | |
| SCHEMBL610497 | 0.81 | BTK (0.70) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481540-B2 | Inhibitors of bruton's tyrosine kinase | HOFFMANN-LA ROCHE INC. (US) | 2013-07-09 | — | — | US | claimed |