Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 15/20 | 0.68 |
| ▸ | PTPRC | P08575 | 2/20 | 0.59 |
| ▸ | PTPN2 | P17706 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410114 | 1.00 | PTPN1 (0.68) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL4410112 | 1.00 | PTPN1 (0.68) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL5021008 | 0.90 | PTPN1 (0.56) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL4412462 | 0.86 | PTPN1 (0.72) | PTPN1PTPRCPTPN2 | |
| SCHEMBL5021027 | 0.85 | PTPN1 (0.71) | PTPN1PTPRCPTPN2 | |
| SCHEMBL2692988 | 0.83 | PTPN1 (0.49) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL2693229 | 0.83 | PTPN1 (0.49) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL15525075 | 0.81 | PTPN1 (1.00) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL15525074 | 0.81 | PTPN1 (1.00) | PTPN1PTPRCPTPN2NPC1RAB9A | |
| SCHEMBL4413820 | 0.78 | PTPN1 (1.00) | PTPN1PTPRCPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481742-B2 | Fused aromatic PTP-1B inhibitors | KANEQ PHARMA INC. (CA) | 2013-07-09 | — | — | US | disclosed |