Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.48 |
| ▸ | CDK9 | P50750 | 5/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 4/20 | 0.48 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.48 |
| ▸ | CDK1 | P06493 | 3/20 | 0.48 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.48 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.48 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.48 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.48 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.48 |
| ▸ | CCND1 | P24385 | 1/20 | 0.48 |
| ▸ | CCND3 | P30281 | 1/20 | 0.48 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.48 |
| ▸ | CDK7 | P50613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2538339 | 0.81 | CCNT1 (0.49) | CDK2CDK9CCNT1CDK5CCNE1 | |
| SCHEMBL15086017 | 0.81 | CCNT1 (0.43) | CDK2CDK9CCNT1CCNE1CDK1 | |
| SCHEMBL2544634 | 0.76 | IKBKB (0.55) | CDK2CCNE1IKBKBCHUK | |
| SCHEMBL2541901 | 0.76 | PLK1 (0.43) | CDK2CDK9CCNT1CDK1CCNB1 | |
| SCHEMBL2539825 | 0.74 | CDK1 (0.53) | CDK2CDK9CCNT1CDK5CCNE1 | |
| SCHEMBL13440365 | 0.72 | AURKA (0.67) | CDK2CDK9CCNT1CDK5CCNE1 | |
| SCHEMBL2547332 | 0.71 | JAK2 (0.53) | CDK2CDK9CCNT1CDK5CCNE1 | |
| SCHEMBL2539545 | 0.70 | ACVR1 (0.49) | CDK2CDK9CCNT1CDK5CCNE1 | |
| SCHEMBL15085747 | 0.70 | DYRK1A (0.41) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL2543307 | 0.70 | CCNT1 (0.54) | CDK2CDK9CCNT1CCNE1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029536-B2 | Fused heterocyclic compounds | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-05-12 | — | — | US | disclosed |
| US-20130172292-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130172292-A1 | FUSED HETEROCYCLIC COMPOUNDS | PDE10A, PDE3A, PDE2A | CDK2 1553/4885CDK9 825/4885CCNT1 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.