⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895447 | 1.00 | — | — | |
| SCHEMBL8346980 | 1.00 | — | — | |
| SCHEMBL12128114 | 1.00 | — | — | |
| SCHEMBL440531 | 1.00 | — | — | |
| SCHEMBL440359 | 1.00 | — | — | |
| SCHEMBL294969 | 1.00 | — | — | |
| SCHEMBL12128113 | 1.00 | — | — | |
| SCHEMBL18314657 | 1.00 | — | — | |
| SCHEMBL27450041 | 0.95 | NPC1 (0.45) | — | |
| SCHEMBL15280991 | 0.95 | NPC1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609919-A2 | c-Met modulators and methods of use | Exelixis Inc. (US) | 2013-07-03 | — | — | EP | disclosed |