Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033681 | 0.75 | — | — | |
| SCHEMBL3138397 | 0.64 | SMN1; SMN2 (0.40) | SMN1; SMN2 | |
| SCHEMBL89369 | 0.63 | — | — | |
| SCHEMBL2478278 | 0.63 | — | — | |
| SCHEMBL18096141 | 0.61 | SMN1; SMN2 (0.52) | SMN1; SMN2 | |
| SCHEMBL20424079 | 0.60 | — | — | |
| SCHEMBL1499936 | 0.60 | OR51E2 (0.42) | SMN1; SMN2 | |
| SCHEMBL14611425 | 0.58 | SMN1; SMN2 (0.39) | SMN1; SMN2 | |
| SCHEMBL12976351 | 0.58 | GAA (0.40) | SMN1; SMN2 | |
| SCHEMBL12681266 | 0.58 | TOP2A (0.35) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420491-B1 | 3 , 5-SUBSTITUED PIPERIDINE COMPOUNDS AS RENIN INHIBITORS | NOVARTIS AG (CH) | 2013-07-03 | — | — | EP | disclosed |