SCHEMBL15088786

SCHEMBL15088786

c1ccc(-c2cc(-c3ccccc3)nc(N3c4cc5c(cc4-c4cccc6cccc3c46)c3cc(-c4ccccc4)ccc3n5-c3ccccn3)c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.38
KDM4E B2RXH2 4/20 0.35
ALDH1A1 P00352 2/20 0.35
GAA P10253 1/20 0.35
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
LMNA P02545 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 2/20 0.32
MAPT P10636 2/20 0.31
MAPK1 P28482 1/20 0.31
HTT P42858 1/20 0.31
UHRF1 Q96T88 1/20 0.31
TP53 P04637 1/20 0.31
TSHR P16473 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089144 0.99 PDE6D (0.37) PDE6DKDM4EALDH1A1GAACASP1
SCHEMBL15088795 0.97 PDE6D (0.37) PDE6DKDM4EALDH1A1GAACASP1
SCHEMBL15089257 0.95 PDE6D (0.35) PDE6DKDM4EALDH1A1GAACASP1
SCHEMBL15088826 0.94 PDE6D (0.36) PDE6DKDM4EALDH1A1GAACASP1
SCHEMBL15089265 0.93 PDE6D (0.39) PDE6D
SCHEMBL15089082 0.92 PDE6D (0.35) PDE6DKDM4EALDH1A1GAAMAPK1
SCHEMBL15089293 0.92 PDE6D (0.42) PDE6DKDM4EALDH1A1GAACASP1
SCHEMBL15089159 0.89 PDE6D (0.40) PDE6D
SCHEMBL15089245 0.89 PDE6D (0.36) PDE6DHTR1AHTR7
SCHEMBL15089285 0.89 PDE6D (0.35) PDE6DKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed