SCHEMBL15088937

SCHEMBL15088937

c1ccc(-c2ccc3c(c2)c2c4c(ccc2n3-c2ccc(-c3ccccn3)cc2)-c2ccc(-c3ccccn3)c3cccc(c23)N4c2ccccc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GRM5 P41594 5/20 0.33
MAPK14 Q16539 1/20 0.32
PDE6D O43924 1/20 0.31
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088948 0.90 GRM5 (0.35) GRM5HTR1AHTR7
SCHEMBL15088967 0.90 GRM5 (0.32) GRM5MAPK14
SCHEMBL15088965 0.88 CYP1A2 (0.33) GRM5MAPK14
SCHEMBL15089071 0.87 CNR2 (0.36) GRM5PDE6D
SCHEMBL15088939 0.87 PDE6D (0.37) PDE6D
SCHEMBL15088938 0.87 TSHR (0.32) GRM5DHODH
SCHEMBL15088958 0.86 METAP1 (0.32) MAPK14
SCHEMBL15088964 0.86 PDE6D (0.35) PDE6D
SCHEMBL15089081 0.85 GRM5 (0.36) GRM5PDE6D
SCHEMBL15088966 0.85 MAPK14 (0.33) GRM5MAPK14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed