SCHEMBL15088940

SCHEMBL15088940

c1ccc(-c2ccc3c(c2)c2c4c(ccc2n3-c2ccc(-c3cccnc3)cn2)-c2ccc(-c3ccccc3)c3cccc(c23)N4c2ccccc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CA P42336 2/20 0.35
CYP11B1 P15538 3/20 0.33
CYP11B2 P19099 3/20 0.33
G6PD P11413 1/20 0.33
MAPK10 P53779 1/20 0.32
KDR P35968 1/20 0.31
MAPT P10636 2/20 0.31
ATM Q13315 1/20 0.31
CYP3A4 P08684 2/20 0.31
LMNA P02545 1/20 0.31
RAF1 P04049 1/20 0.31
CYP1A2 P05177 1/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31
MAPK14 Q16539 1/20 0.31
TDP2 O95551 1/20 0.31
ICMT O60725 1/20 0.30
PIM1 P11309 1/20 0.30
PIM3 Q86V86 1/20 0.30
PIM2 Q9P1W9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089071 0.89 CNR2 (0.36) KDRMAPTGRM5
SCHEMBL15088967 0.88 GRM5 (0.32) MAPTMAPK14GRM5
SCHEMBL15089279 0.87 PDE6D (0.37) CYP11B1CYP11B2G6PDMAPTMAPK1
SCHEMBL15088957 0.86 MEN1 (0.34) PIK3CAMAPTLMNAMAPK1
SCHEMBL15088834 0.85 PIK3CA (0.37) PIK3CACYP11B1CYP11B2G6PDMAPK10
SCHEMBL15088944 0.85 PIK3CA (0.37) PIK3CAMAPTATM
SCHEMBL15089308 0.84 HTT (0.37) G6PDMAPTMAPK1MAPK14
SCHEMBL15088964 0.84 PDE6D (0.35) ATM
SCHEMBL15089345 0.83 HTT (0.38) CYP11B1CYP11B2G6PDMAPTMAPK1
SCHEMBL15088939 0.83 PDE6D (0.37) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed