SCHEMBL15088949

SCHEMBL15088949

c1ccc(-c2ccc3c4c(cccc24)N(c2ccccc2)c2c-3ccc3c2c2ccccc2n3-c2ccc(-n3c4ccccc4c4ccccc43)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
PDE6D O43924 1/20 0.34
MAPK14 Q16539 1/20 0.33
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
PTPN1 P18031 1/20 0.31
HDAC4 P56524 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088950 0.92 KDM4E (0.37) L3MBTL1KDM4EATMPDE6D
SCHEMBL15088959 0.91 ATM (0.34) L3MBTL1KDM4EATMPDE6DMAPK14
SCHEMBL15088939 0.90 PDE6D (0.37) L3MBTL1KDM4EATMPDE6D
SCHEMBL15088961 0.89 PDE6D (0.34) L3MBTL1KDM4EATMPDE6DMAPK14
SCHEMBL15088964 0.89 PDE6D (0.35) L3MBTL1KDM4EATMPDE6D
SCHEMBL15088974 0.88 KDM4E (0.35) L3MBTL1KDM4EATMPDE6DMAPK14
SCHEMBL15089290 0.87 KDM4E (0.43) L3MBTL1KDM4EATMPDE6DKMT2A
SCHEMBL15089300 0.86 PDE6D (0.51) L3MBTL1KDM4EATMPDE6DKMT2A
SCHEMBL15088975 0.85 KDM4E (0.32) L3MBTL1KDM4EATMPDE6D
SCHEMBL15089271 0.84 KDM4E (0.41) L3MBTL1KDM4EATMPDE6DKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed