SCHEMBL15088998

SCHEMBL15088998

CC1(C)c2ccccc2-c2cc3c(cc21)N(c1ccccn1)c1ccc(-c2ccccn2)c2cccc-3c12

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPT P10636 2/20 0.38
HTT P42858 2/20 0.38
TSHR P16473 1/20 0.38
CASP1 P29466 1/20 0.38
HBB P68871 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPC1 O15118 1/20 0.34
S1PR4 O95977 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
XBP1 P17861 1/20 0.34
S1PR1 P21453 1/20 0.34
CCR6 P51684 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
HTR2C P28335 1/20 0.34
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15088999 0.89 HTR2C (0.33) HTR2CBRD4PDK2
SCHEMBL15088987 0.88 HTR2C (0.33) HTR2CPDK2
SCHEMBL15089179 0.87 MEN1 (0.37) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15089008 0.86 PDK2 (0.35) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15089096 0.86 HTT (0.32) MAPTHTTHTR2CGAABRD4
SCHEMBL15089004 0.83 KDM4E (0.45) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL15089005 0.80 CNR2 (0.36) KDM4EALDH1A1MAPTCASP1HTR2C
SCHEMBL15089227 0.79 PDK2 (0.35) MEN1KMT2AKDM4EALDH1A1MAPT
SCHEMBL12442290 0.78 BRD4 (0.40) KDM4EALDH1A1MAPTHTTSMN1; SMN2
SCHEMBL12442287 0.78 BRD4 (0.40) KDM4EALDH1A1MAPTHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed