SCHEMBL15089145

SCHEMBL15089145

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2ccccn2)N(c2cccc(-c3ccc5c(c3)c3ccccc3n5-c3ccccc3)n2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.37

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.37
KDM4E B2RXH2 3/20 0.32
ALDH1A1 P00352 2/20 0.32
GAA P10253 1/20 0.32
MEN1 O00255 2/20 0.32
LMNA P02545 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
MAPT P10636 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
UHRF1 Q96T88 1/20 0.30
NPY5R Q15761 1/20 0.30
CASP1 P29466 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089129 0.97 PDE6D (0.34) PDE6DKDM4EALDH1A1GAAMEN1
SCHEMBL15089241 0.96 PDE6D (0.33) PDE6DKDM4EALDH1A1GAAMEN1
SCHEMBL15089371 0.94 PDE6D (0.40) PDE6DKDM4E
SCHEMBL15089065 0.93 PDE6D (0.34) PDE6DKDM4EALDH1A1GAANPY5R
SCHEMBL15088925 0.92 PDE6D (0.37) PDE6DKDM4E
SCHEMBL15089161 0.91 PDE6D (0.39) PDE6DKDM4EALDH1A1GAAMEN1
SCHEMBL15089136 0.90 PDE6D (0.43) PDE6DKDM4EALDH1A1GAAMEN1
SCHEMBL15089357 0.89 PDE6D (0.36) PDE6DKDM4EALDH1A1GAACASP1
SCHEMBL15089354 0.88 KDM4E (0.39) PDE6DKDM4EALDH1A1GAAMEN1
SCHEMBL15089293 0.88 PDE6D (0.42) PDE6DKDM4EALDH1A1GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed