SCHEMBL15089189

SCHEMBL15089189

c1ccc(-c2ccc(N3c4cc5c(cc4-c4cccc6cccc3c46)-c3ccccc3C5(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.51
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
OPRK1 P41145 1/20 0.34
KMT2A Q03164 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089213 0.88 KDM4E (0.40) PDE6DKDM4EMEN1LMNAMAPT
SCHEMBL15089181 0.86 PDE6D (0.37) PDE6DKDM4EMEN1LMNAMAPT
SCHEMBL15089089 0.86 PDE6D (0.37) PDE6D
SCHEMBL15088990 0.85 PDE6D (0.52) PDE6DMEN1KMT2A
SCHEMBL15089186 0.83 PDE6D (0.36) PDE6DKDM4EMEN1LMNAMAPT
SCHEMBL17402634 0.83 PDE6D (0.46) PDE6D
SCHEMBL18859359 0.83 PDE6D (0.41) PDE6D
SCHEMBL15089043 0.83 HTT (0.43) PDE6DKDM4EMEN1LMNAMAPT
SCHEMBL15089180 0.83 PDE6D (0.37) PDE6DKDM4EMEN1LMNAMAPT
SCHEMBL15089225 0.83 PDE6D (0.35) PDE6DKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed