SCHEMBL15089220

SCHEMBL15089220

c1ccc(C2(c3ccccc3)c3ccccc3-c3cc4c(cc32)N(c2ccncc2)c2ccc(-c3ccccn3)c3cccc-4c23)cc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30
CDK8 P49336 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089044 0.90 CDK8 (0.32) CDK8
SCHEMBL15089179 0.89 MEN1 (0.37) PDK2
SCHEMBL15088999 0.87 HTR2C (0.33) PDK2
SCHEMBL15089227 0.85 PDK2 (0.35) PDK2
SCHEMBL15089188 0.83
SCHEMBL15089101 0.82 PDK2 (0.34) PDK2
SCHEMBL15089213 0.81 KDM4E (0.40) RXFP1
SCHEMBL15089202 0.81 PDK2 (0.34) PDK2
SCHEMBL15089228 0.79 CYP11B1 (0.35) PDK2CDK8
SCHEMBL15089096 0.78 HTT (0.32) PDK2CDK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed