SCHEMBL15089280

SCHEMBL15089280

c1ccc(N2c3cccc4cccc(c34)-c3ccc4c(c32)c2ccccc2n4-c2cccc(-n3c4ccccc4c4ccccc43)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.39
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ATM Q13315 1/20 0.39
ALDH1A1 P00352 5/20 0.32
USP2 O75604 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CES2 O00748 1/20 0.31
BCHE P06276 1/20 0.31
GAA P10253 1/20 0.31
CES1 P23141 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
POLB P06746 2/20 0.31
APOBEC3A P31941 1/20 0.31
RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089290 0.94 KDM4E (0.43) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089271 0.94 KDM4E (0.41) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089276 0.92 PDE6D (0.44) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089301 0.91 PDE6D (0.41) PDE6DKDM4EL3MBTL1ATM
SCHEMBL15088932 0.89 PDE6D (0.36) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089273 0.89 PDE6D (0.44) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089300 0.89 PDE6D (0.51) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089373 0.89 PDE6D (0.40) PDE6DKDM4EL3MBTL1ATMALDH1A1
SCHEMBL15089322 0.88 HTT (0.42) PDE6DKDM4EL3MBTL1ATMMAPT
SCHEMBL15089297 0.88 KDM4E (0.40) PDE6DKDM4EL3MBTL1ATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed