SCHEMBL15089287

SCHEMBL15089287

c1ccc(-c2ccc3c(c2)c2cc4c(cc2n3-c2cccc(-n3c5ccccc5c5ccccc53)n2)N(c2cccc(-n3c5ccccc5c5ccccc53)n2)c2cccc3cccc-4c23)cc1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.43
POLB P06746 1/20 0.33
TSPO P30536 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
NPY5R Q15761 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15089161 0.94 PDE6D (0.39) PDE6DMEN1KMT2A
SCHEMBL15088924 0.91 PDE6D (0.36) PDE6DPOLBMEN1KMT2A
SCHEMBL15088849 0.91 PDE6D (0.33) PDE6DTSPONPY5R
SCHEMBL15089371 0.91 PDE6D (0.40) PDE6D
SCHEMBL15089092 0.88 PDE6D (0.39) PDE6DPOLBMEN1KMT2A
SCHEMBL15089061 0.87 NPY5R (0.35) PDE6DPOLBMEN1KMT2ANPY5R
SCHEMBL15088925 0.87 PDE6D (0.37) PDE6DPOLB
SCHEMBL15089293 0.87 PDE6D (0.42) PDE6DPOLBMEN1KMT2A
SCHEMBL15089253 0.86 KDM4E (0.36) PDE6DPOLBMEN1KMT2A
SCHEMBL15089274 0.86 PDE6D (0.40) PDE6D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013100497-A1 ORGANIC LIGHT-EMITTING COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 주식회사 두산 (KR) 2013-07-04 WO disclosed