Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508493 | 0.91 | HTR2C (0.44) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL1508949 | 0.90 | HTR2C (0.44) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL1508854 | 0.86 | HTR2C (0.52) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL1509134 | 0.84 | SMN1; SMN2 (0.45) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL26720000 | 0.74 | SMN1; SMN2 (0.46) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL30429792 | 0.73 | HTR2C (0.44) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| Hydrochloric Acid SCHEMBL17459607 | 0.73 | — | — | |
| SCHEMBL29514412 | 0.72 | SMN1; SMN2 (0.44) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL18410564 | 0.72 | HTR2C (0.57) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 | |
| SCHEMBL9546620 | 0.72 | HTR2C (0.57) | HTR2CSMN1; SMN2NPC1RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |