Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.38 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.37 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 2/20 | 0.31 |
| ▸ | ARG2 | P78540 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1508726 | 1.00 | DPP4 (0.38) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL23340946 | 0.85 | DPP4 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1508935 | 0.85 | DPP4 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1508626 | 0.85 | DPP4 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1508930 | 0.82 | DPP4 (0.38) | DPP4 | |
| SCHEMBL1508907 | 0.82 | DPP4 (0.38) | DPP4 | |
| SCHEMBL1508928 | 0.82 | DPP4 (0.38) | DPP4 | |
| SCHEMBL1508911 | 0.82 | DPP4 (0.38) | DPP4 | |
| SCHEMBL2492932 | 0.81 | CTSC (0.35) | — | |
| SCHEMBL2490743 | 0.81 | CTSC (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2298778-A1 | IMIDAZOTHIAZOLE DERIVATIVE HAVING 4,7-DIAZASPIROÝ2.5¨OCTANE RING STRUCTURE | Daiichi Sankyo Company, Limited (JP) | 2011-03-23 | — | — | EP | disclosed |