⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14932121 | 0.72 | — | — | |
| SCHEMBL1093730 | 0.59 | — | — | |
| SCHEMBL616019 | 0.53 | — | — | |
| Hydrochloric Acid SCHEMBL28869240 | 0.51 | — | — | |
| SCHEMBL336815 | 0.50 | — | — | |
| SCHEMBL654468 | 0.50 | — | — | |
| SCHEMBL200660 | 0.48 | — | — | |
| SCHEMBL10990 | 0.45 | — | — | |
| SCHEMBL55071 | 0.45 | — | — | |
| SCHEMBL7021498 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3455224-B1 | SUBSTITUTED 5,6,7,8-TETRAHYDRO[1,2,4]TRIAZOLO[4,3-A]PYRIDINE-3(2H)-ONES AND 2,5,6,7-TETRAHYDRO-3H-PYRROLO[2,1-C][1,2,4]TRIAZOL-3-ONES, AND USE THEREOF | BAYER AG (DE) | 2024-03-27 | — | — | EP | claimed |
| WO-2023205645-A1 | BICYCLIC COMPOUNDS | ALIGOS THERAPEUTICS, INC. (US) | 2023-10-26 | — | — | WO | claimed |
| CN-113735842-B | 1,2, 4-triazole Schiff base thioether derivatives, and preparation method and application thereof | 河北农业大学 | 2023-01-31 | — | — | CN | claimed |
| US-11337973-B2 | Substituted [1,2,4]triazolo[4,3-A]pyrazines as prolyl endopeptidase inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | claimed |
| EP-3707141-B1 | SUBSTITUTED 2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONES AND USE OF SAME | BAYER AG (DE) | 2021-12-22 | — | — | EP | claimed |
| CN-113735842-A | 1,2, 4-triazole Schiff base thioether derivatives, and preparation method and application thereof | 河北农业大学 | 2021-12-03 | — | — | CN | claimed |
| CN-113574055-A | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2021-10-29 | — | — | CN | claimed |
| CN-113412258-A | PCSK9 inhibitors and methods of use thereof | 阿斯利康(瑞典)有限公司 | 2021-09-17 | — | — | CN | claimed |
| CN-109476658-B | Substituted 5,6,7, 8-tetrahydro [1,2,4] triazolo [4,3-a ] pyridin-3 (2H) -ones and 2,5,6, 7-tetrahydro-3H-pyrrolo [2,1-c ] [1,2,4] triazol-3-ones and uses thereof | 拜耳公司 | 2021-08-10 | — | — | CN | claimed |
| US-20200375986-A1 | SUBSTITUTED 2,4-DIHYDRO-3H-1,2,4-TRIAZOL-3-ONES AND USE OF SAME | BAYER AKTIENGESELLSCHAFT (DE) | 2020-12-03 | — | — | US | claimed |
| EP-1453516-A2 | NOVEL TRI-SUBSTITUTED PYRIMIDINES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-09-08 | — | — | EP | claimed |
| US-6613761-B1 | (3R,5S)-N- methanesulfonyl-7-chloro-5-(2,3-dimethoxyphenyl) -1-(3-hydroxy-2,2-dimethylpropyl)-2-oxo-1,2,3,5-tetrahydro-4, 1-benzoxazepine-3-acetamide, used as antilipemic agents and enzyme inhibitors | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-02 | — | — | US | claimed |
| US-20030134838-A1 | Trisubstituted pyrimidines | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2003-07-17 | — | — | US | claimed |
| WO-2003032994-A2 | NOVEL TRI-SUBSTITUTED PYRIMIDINES, METHOD FOR PRODUCTION AND USE THEREOF AS MEDICAMENT | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2003-04-24 | — | — | WO | claimed |
| WO-2001089447-A2 | ANTIFUNGAL SUBSTITUTED PROPYL TRIAZOLE COMPOUND, ITS SALT, AND PREPARATION METHODS THEREOF | SECOND MILITARY MEDICAL UNIVERSITY OF PLA. (CN) | 2001-11-29 | — | — | WO | claimed |
| WO-2001010853-A1 | SUBSTITUTED 2-IMINO-THIAZOLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-15 | — | — | WO | claimed |
| EP-0751944-B1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL IND LTD (JP) | 2000-12-20 | — | — | EP | claimed |
| US-5955481-A | Pyridine type thiazolidines | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-09-21 | — | — | US | claimed |
| US-5610121-A | HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | claimed |
| WO-1995026347-A1 | THIAZOLIDINES AND OXAZOLIDINES SUBSTITUTED BY A PYRIDINE RING AND THEIR USE AS HYPOGLYCEMIC AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1995-10-05 | — | — | WO | claimed |