SCHEMBL15090239

SCHEMBL15090239

Cc1ccc(O[C@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)cc1

nearest known ligand 0.75

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYR P14679 2/20 0.75
POLB P06746 1/20 0.68
SLC5A2 P31639 2/20 0.62
EPHX2 P34913 1/20 0.60
CA12 O43570 3/20 0.57
CA9 Q16790 3/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 1/20 0.57
SLC5A1 P13866 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5027844 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL14120000 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL20056390 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL16788465 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL10102997 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL24760381 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL16788464 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL10102996 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL10103035 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12
SCHEMBL15061156 1.00 TYR (0.75) TYRPOLBSLC5A2EPHX2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175044-B2 Derivatives of glyco-CF2-serine and glyco-CF2-threonine TFCHEM (FR) 2015-11-03 US disclosed
US-20130171180-A1 DERIVATIVES OF GLYCO-CF2-SERINE AND GLYCO-CF2-THREONINE TFCHEM (FR) 2013-07-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130171180-A1 DERIVATIVES OF GLYCO-CF2-SERINE AND GLYCO-CF2-THREONINE PTMS, SLC5A2, INF2 TYR 2120/4885POLB 4428/4885SLC5A2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.