SCHEMBL15090246

SCHEMBL15090246

C=CC[C@]1(C(=O)OC)C[C@@H](O)[C@@H](NC(C)=O)C([C@H](O)[C@H](O)CO)O1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ NANP Q8TBE9 3/20 0.50
▸ MAG P20916 4/20 0.39
▸ NEU4 Q8WWR8 2/20 0.39
▸ NEU3 Q9UQ49 2/20 0.39
▸ NEU2 Q9Y3R4 2/20 0.39
▸ NEU1 Q99519 1/20 0.39
▸ SIGLEC7 Q9Y286 1/20 0.38
▸ L3MBTL1 Q9Y468 1/20 0.38
▸ SELL P14151 1/20 0.38
▸ SELP P16109 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30484530 0.90 NANP (0.49) NANPMAGNEU4NEU3NEU2
SCHEMBL31695272 0.88 NANP (0.39) NANPMAGSIGLEC7L3MBTL1SELL
SCHEMBL31695026 0.87 NANP (0.48) NANPNEU4NEU3NEU2SIGLEC7
SCHEMBL15090252 0.87 NANP (0.48) NANPNEU4NEU3NEU2SIGLEC7
SCHEMBL16362518 0.87 NANP (0.48) NANPNEU4NEU3NEU2SIGLEC7
SCHEMBL15087687 0.82 NANP (0.58) NANPMAGSIGLEC7SELLSELP
SCHEMBL18357290 0.82 NANP (0.58) NANPMAGSIGLEC7SELLSELP
SCHEMBL16839997 0.82 NANP (0.58) NANPMAGSIGLEC7SELLSELP
SCHEMBL24630166 0.81 NANP (0.58) NANPMAGNEU4NEU3NEU2
SCHEMBL21162637 0.81 NANP (0.58) NANPMAGNEU4NEU3NEU2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2797946-B1 SIALIC ACID DIMERS BROSSMER REINHARD (DE) 2016-05-04 — — EP disclosed
US-9260467-B2 Sialic acid dimers BROSSMER REINHARD (DE) 2016-02-16 — — US disclosed
US-9260467-B2 Sialic acid dimers BROSSMER REINHARD (DE) 2016-02-16 — — US disclosed
US-20150005245-A1 Sialic Acid Dimers BROSSMER REINHARD (DE) 2015-01-01 — — US disclosed
US-20150005245-A1 Sialic Acid Dimers BROSSMER REINHARD (DE) 2015-01-01 — — US disclosed
WO-2013097942-A1 SIALIC ACID DIMERS BROSSMER REINHARD (DE) 2013-07-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150005245-A1 Sialic Acid Dimers SIGLEC9, SIGLEC7, NEU2 NANP 333/4885MAG 503/4885NEU4 7/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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