Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | MAPK14 | Q16539 | 9/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15093277 | 1.00 | CYP3A4 (0.65) | CYP3A4MAPK14 | |
| SCHEMBL15093286 | 1.00 | CYP3A4 (0.65) | CYP3A4MAPK14 | |
| SCHEMBL15093380 | 0.96 | CYP3A4 (0.67) | CYP3A4MAPK14 | |
| SCHEMBL15093695 | 0.96 | CYP3A4 (0.67) | CYP3A4MAPK14 | |
| SCHEMBL15093696 | 0.96 | CYP3A4 (0.67) | CYP3A4MAPK14 | |
| SCHEMBL15099656 | 0.94 | CYP3A4 (0.56) | CYP3A4MAPK14 | |
| SCHEMBL15099575 | 0.93 | CYP3A4 (0.67) | CYP3A4MAPK14 | |
| SCHEMBL15099752 | 0.93 | CYP3A4 (0.67) | CYP3A4MAPK14 | |
| SCHEMBL1699652 | 0.93 | CYP3A4 (0.68) | CYP3A4MAPK14 | |
| SCHEMBL1699741 | 0.93 | CYP3A4 (0.68) | CYP3A4MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284323-B2 | Naphthalene acetic acid derivatives against HIV infection | GILEAD SCIENCES, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| WO-2013103738-A1 | NAPTHALENE ACETIC ACID DERIVATIVES AGAINST HIV INFECTION | GILEAD SCIENCES, INC. (US) | 2013-07-11 | — | — | WO | disclosed |