Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Aminobenzoic Acid SCHEMBL1802563 | 0.87 | PBRM1 (0.60) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL8846571 | 0.87 | PBRM1 (0.60) | PBRM1CA12CA1CA2CA6 | |
| Isophthalic Acid SCHEMBL11490530 | 0.87 | CA12 (0.54) | CA12CA1CA2CA6CA9 | |
| 3-Aminobenzoic Acid SCHEMBL8003706 | 0.87 | PBRM1 (0.69) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL27648 | 0.87 | PBRM1 (0.69) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL29367812 | 0.87 | PBRM1 (0.69) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL11796891 | 0.85 | PBRM1 (0.67) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL1478325 | 0.85 | PBRM1 (0.67) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL2296707 | 0.85 | PBRM1 (0.67) | PBRM1CA12CA1CA2CA6 | |
| 3-Aminobenzoic Acid SCHEMBL2888635 | 0.85 | PBRM1 (0.67) | PBRM1CA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2289962-A2 | Polyurea compositions and compounds for the preparation thereof | Sawyer, Kenneth I. (US) | 2011-03-02 | — | — | EP | claimed |
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | Sawyer, Kenneth I. (US) | 2008-08-14 | — | — | US | claimed |
| EP-1751206-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | Sawyer, Kenneth I. (US) | 2007-02-14 | — | — | EP | claimed |
| WO-2005113487-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | SAWYER KENNETH I (US) | 2005-12-01 | — | — | WO | claimed |
| EP-2289962-A2 | Polyurea compositions and compounds for the preparation thereof | Sawyer, Kenneth I. (US) | 2011-03-02 | — | — | EP | disclosed |
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | Sawyer, Kenneth I. (US) | 2008-08-14 | — | — | US | disclosed |
| EP-1751206-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | Sawyer, Kenneth I. (US) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005113487-A2 | POLYUREA COMPOSITIONS AND COMPOUNDS FOR THE PREPARATION THEREOF | SAWYER KENNETH I (US) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080194859-A1 | Polyurea Compositions and Compounds for the Preparation Thereof | PUF60, PCNA, PARG | PBRM1 75/4885CA12 3968/4885CA1 4498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.