Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 5/20 | 0.81 |
| ▸ | TYMS | P04818 | 3/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.81 |
| ▸ | MEN1 | O00255 | 1/20 | 0.81 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.81 |
| ▸ | POLB | P06746 | 1/20 | 0.81 |
| ▸ | GAA | P10253 | 1/20 | 0.81 |
| ▸ | HPGD | P15428 | 1/20 | 0.81 |
| ▸ | TSHR | P16473 | 1/20 | 0.81 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.81 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.81 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.58 |
| ▸ | DHFR | P00374 | 5/20 | 0.57 |
| ▸ | GART | P22102 | 2/20 | 0.53 |
| ▸ | ATIC | P31939 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174303 | 1.00 | AKR1B1 (0.81) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL28937191 | 0.96 | AKR1B1 (0.77) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL28226859 | 0.94 | AKR1B1 (0.80) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL29423667 | 0.93 | AKR1B1 (0.79) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL11897941 | 0.93 | AKR1B1 (0.79) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL30634933 | 0.93 | AKR1B1 (0.79) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL869875 | 0.93 | AKR1B1 (0.79) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL6679712 | 0.92 | AKR1B1 (0.77) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL16150298 | 0.92 | AKR1B1 (0.77) | AKR1B1TYMSKDM4EMEN1ALDH1A1 | |
| SCHEMBL14323639 | 0.92 | AKR1B1 (0.77) | AKR1B1TYMSKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108273068-B | Epigallocatechin gallate-loaded folic acid targeting vector and preparation method and application thereof | 浙江大学 | 2020-09-18 | — | — | CN | disclosed |
| CN-108144068-B | Folic acid targeting vector loaded with mono-substituted epigallocatechin gallate palmitate as well as preparation method and application thereof | 浙江大学 | 2020-08-18 | — | — | CN | disclosed |
| US-9180202-B2 | Polyoxazoline polymers and methods for their preparation, conjugates of these polymers and medical uses thereof | UNIVERSITEIT GENT (BE) | 2015-11-10 | — | — | US | disclosed |
| US-20150025196-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIVERSITEIT GENT (BE) | 2015-01-22 | — | — | US | disclosed |
| EP-2800773-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | Universiteit Gent (BE) | 2014-11-12 | — | — | EP | disclosed |
| WO-2013103297-A1 | POLYOXAZOLINE POLYMERS AND METHODS FOR THEIR PREPARATION, CONJUGATES OF THESE POLYMERS AND MEDICAL USES THEREOF | UNIVERSITEIT GENT (BE) | 2013-07-11 | — | — | WO | disclosed |