Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 17/20 | 0.65 |
| ▸ | BIRC3 | Q13489 | 8/20 | 0.65 |
| ▸ | BIRC2 | Q13490 | 12/20 | 0.52 |
| ▸ | CASP9 | P55211 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113579 | 1.00 | XIAP (0.65) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2632146 | 1.00 | XIAP (0.65) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2115448 | 0.94 | XIAP (0.63) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL10284302 | 0.94 | XIAP (0.63) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2631840 | 0.93 | XIAP (0.63) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2115252 | 0.93 | XIAP (0.63) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL13048223 | 0.90 | XIAP (0.62) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2631837 | 0.90 | XIAP (0.62) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2632160 | 0.90 | XIAP (0.62) | XIAPBIRC3BIRC2CASP9 | |
| SCHEMBL2113355 | 0.90 | XIAP (0.62) | XIAPBIRC3BIRC2CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481495-B2 | IAP inhibitors | TETRALOGIC PHARMACEUTICALS CORPORATION (US) | 2013-07-09 | — | — | US | disclosed |