Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.31 |
| ▸ | TFPI2 | P48307 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208292 | 1.00 | MEN1 (0.31) | MEN1KMT2ALMNATP53NFKB1 | |
| SCHEMBL2759295 | 1.00 | MEN1 (0.31) | MEN1KMT2ALMNATP53NFKB1 | |
| SCHEMBL12023938 | 0.92 | — | — | |
| SCHEMBL8239541 | 0.87 | KAT2A (0.35) | MEN1KMT2ATP53SMN1; SMN2CYP2C9 | |
| SCHEMBL15764751 | 0.86 | — | — | |
| SCHEMBL11757369 | 0.86 | — | — | |
| SCHEMBL16421242 | 0.86 | — | — | |
| SCHEMBL16377125 | 0.86 | — | — | |
| SCHEMBL14185119 | 0.83 | — | — | |
| SCHEMBL18900921 | 0.83 | TP53 (0.40) | MEN1KMT2ATP53KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9376413-B1 | Succinic anhydrides from epoxides | CORNELL UNIVERSITY (US) | 2016-06-28 | — | — | US | disclosed |
| US-9376413-B1 | Succinic anhydrides from epoxides | CORNELL UNIVERSITY (US) | 2016-06-28 | — | — | US | disclosed |
| US-8921581-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8921581-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| US-8481756-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481756-B1 | Succinic anhydrides from epoxides | CORNELL RESEARCH FOUNDATION, INC. (US) | 2013-07-09 | — | — | US | disclosed |