Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14076029 | 0.81 | APP (0.60) | APP | |
| SCHEMBL14076025 | 0.80 | APP (0.59) | APP | |
| SCHEMBL14067491 | 0.76 | APP (0.54) | APP | |
| SCHEMBL14390022 | 0.74 | APP (0.72) | APP | |
| SCHEMBL14390106 | 0.74 | APP (0.67) | APP | |
| SCHEMBL4938134 | 0.74 | APP (0.54) | APP | |
| SCHEMBL4921510 | 0.71 | APP (0.52) | APP | |
| SCHEMBL4914340 | 0.71 | APP (0.52) | APP | |
| SCHEMBL14067308 | 0.71 | APP (0.52) | APP | |
| SCHEMBL12926171 | 0.71 | CSNK1D (0.40) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44354-E1 | Amyloid plaque aggregation inhibitors and diagnostic imaging agents | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-07-09 | — | — | US | disclosed |