SCHEMBL1509673

SCHEMBL1509673

O=Cc1ccccc1Cl.O=Cc1ccccc1Cl

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.63
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
LMNA P02545 2/20 0.63
THRB P10828 1/20 0.63
BLM P54132 1/20 0.63
ALDH1A1 P00352 4/20 0.56
TSHR P16473 2/20 0.50
TRIM24 O15164 1/20 0.50
TRIM33 Q9UPN9 1/20 0.50
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
GSR P00390 1/20 0.45
DYRK2 Q92630 1/20 0.45
TRPA1 O75762 1/20 0.45
HPGD P15428 1/20 0.44
HTT P42858 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NFE2L2 Q16236 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29815450 1.00
SCHEMBL97422 1.00
Methane SCHEMBL10926734 0.97 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
SCHEMBL29924187 0.97 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
Hydrochloric Acid SCHEMBL10816378 0.97 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
SCHEMBL29684596 0.97 TDP1 (0.60) TDP1MEN1KMT2ALMNATHRB
Hydrochloric Acid SCHEMBL11144927 0.95 TDP1 (0.57) TDP1MEN1KMT2ALMNATHRB
Ethane SCHEMBL2154274 0.95 TDP1 (0.57) TDP1MEN1KMT2ALMNATHRB
Methyl Alcohol SCHEMBL28778721 0.93 TDP1 (0.55) TDP1MEN1KMT2ALMNATHRB
Naphthalene SCHEMBL10495715 0.93 TDP1 (0.55) TDP1MEN1KMT2ALMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1160329-B1 An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin NIPPON CATALYTIC CHEM IND (JP) 2011-04-06 EP disclosed
EP-2295592-A1 An enzyme reaction method and a method for enzymatically producing an optically active cyanohydrin Nippon Shokubai Co., Ltd. (JP) 2011-03-16 EP disclosed