Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.71 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.68 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.68 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 2/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL410578 | 0.98 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2TBXAS1ALPG | |
| SCHEMBL10247417 | 0.91 | CYP19A1 (0.68) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| Hydrochloric Acid SCHEMBL412291 | 0.89 | CYP19A1 (0.67) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL11131296 | 0.88 | CYP19A1 (0.70) | CYP19A1CYP11B1CYP11B2TBXAS1ALPG | |
| SCHEMBL12045380 | 0.88 | CYP19A1 (0.70) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL27559825 | 0.88 | CYP19A1 (0.79) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL11362294 | 0.87 | CYP19A1 (0.65) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| Hydrochloric Acid SCHEMBL9996128 | 0.87 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2TBXAS1ALPG | |
| Hydrochloric Acid SCHEMBL9996048 | 0.87 | CYP19A1 (0.69) | CYP19A1CYP11B1CYP11B2ALPGALPI | |
| SCHEMBL11020478 | 0.85 | CYP19A1 (0.63) | CYP19A1CYP11B1CYP11B2ALPGALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 126 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017077550-A1 | A METAL FREE PROCESS FOR THE PREPARATION OF ALPHA-SUBSTITUTED CARBONYL COMPOUNDS FROM ALKENES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-05-11 | — | — | WO | claimed |
| CN-1013444-B | PROCESS FOR THE PREPARATION OF A NOVEL CLASS OF HYPOGLYCEMIC AGENTS | LILLY CO ELI (US) | 1991-08-07 | — | — | CN | claimed |
| EP-0182533-B1 | 3-(2-ARYL-2-OXOETHYL)-IMIDAZOLIUM SALTS AS HYPOGLYCEMIC AGENTS | ELI LILLY AND COMPANY (US) | 1989-09-20 | — | — | EP | claimed |
| EP-0309953-A1 | 5-Substituted-3-phenyl-3-(1H-imidazol-1-ylmethyl)-2-methyl-isoxazolidines | FISONS CORPORATION (US) | 1989-04-05 | — | — | EP | claimed |
| CN-85108115-A | The preparation method of new low point hypoglycaemic agent | — | 1986-07-30 | — | — | CN | claimed |
| EP-0182533-A2 | 3-(2-Aryl-2-oxoethyl)-imidazolium salts as hypoglycemic agents | ELI LILLY AND COMPANY (US) | 1986-05-28 | — | — | EP | claimed |
| JP-59013762-A | — | — | None | — | — | JP | disclosed |
| CN-115073448-A | Application of fused ring heterocyclic compound or pharmaceutically acceptable salt thereof in preparation of medicine for treating cerebral apoplexy | 浙江大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-115073449-A | Fused ring heterocyclic compound and application thereof, and pharmaceutical composition containing fused ring heterocyclic compound and application thereof | 浙江大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-115068471-A | Application of fused ring heterocyclic compound or pharmaceutically acceptable salt thereof in preparation of drugs for treating Parkinson's disease | 浙江大学 | 2022-09-20 | — | — | CN | disclosed |
| WO-2022188876-A1 | FUSED RING HETEROCYCLIC COMPOUND AND APPLICATION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND APPLICATION THEREOF | 浙江大学 | 2022-09-15 | — | — | WO | disclosed |
| CN-109320458-B | Diaryl imidazole-containing compound, preparation method and medical application thereof | 中国药科大学 | 2022-05-31 | — | — | CN | disclosed |
| US-11048168-B2 | Permanent dielectric compositions containing photoacid generator and base | PROMERUS, LLC (US) | 2021-06-29 | — | — | US | disclosed |
| EP-0061794-A1 | Antimicrobial imidazole derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 1982-10-06 | — | — | EP | disclosed |
| US-4351948-A | Imidazole hydrazone derivatives | G.D. SEARLE & CO. (US) | 1982-09-28 | — | — | US | disclosed |
| EP-0055059-A1 | Diazole and triazole derivatives, processes for their preparation and anti-microbial compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-06-30 | — | — | EP | disclosed |
| EP-0049913-A2 | New ethenylimidazole derivatives, processes for their preparation and pharmaceutical compositions containing them; intermediates, useful in their preparation and a process for the preparation thereof | GIST-BROCADES N.V. (NL) | 1982-04-21 | — | — | EP | disclosed |
| US-4210656-A | BACTERICIDES, FUNGICIDES | SIEGFRIED AKTIENGESELLSCHAFT (CH) | 1980-07-01 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |