SCHEMBL15097890

SCHEMBL15097890

CCOC(=O)COc1ccc(SC(Cc2ccc(-c3ccccc3)cc2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1C

nearest known ligand 0.86

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.86
PPARA Q07869 4/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15097268 0.97 PPARD (0.82) PPARDPPARA
SCHEMBL15097846 0.95 PPARD (0.78) PPARDPPARA
SCHEMBL15097818 0.94 PPARD (0.78) PPARDPPARA
SCHEMBL15097176 0.93 PPARD (1.00) PPARDPPARA
SCHEMBL15097897 0.92 PPARD (0.77) PPARDPPARA
SCHEMBL15142407 0.92 PPARD (0.72) PPARDPPARA
SCHEMBL15142620 0.92 PPARD (0.72) PPARDPPARA
SCHEMBL15097790 0.91 PPARD (0.74) PPARDPPARA
SCHEMBL14899478 0.90 PPARD (0.87) PPARDPPARA
SCHEMBL15097845 0.90 PPARD (0.72) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130197043-A1 USE OF THE FETAL REPROGRAMMING OF A PPAR AGONIST SNU R&DB FOUNDATION (KR) 2013-08-01 US disclosed
EP-2612669-A2 USE OF THE FETAL REPROGRAMMING OF A PPAR AGONIST SNU R & DB Foundation (KR) 2013-07-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130197043-A1 USE OF THE FETAL REPROGRAMMING OF A PPAR AGONIST PPARD, PPARA, PPARG PPARD 1/4885PPARA 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.