Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14302495 | 0.82 | KMT2A (0.66) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL13979931 | 0.82 | KMT2A (0.66) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL9939512 | 0.82 | KMT2A (0.66) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL9938489 | 0.82 | KMT2A (0.66) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL12414687 | 0.81 | KMT2A (0.64) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL31655448 | 0.81 | KMT2A (0.64) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL27506594 | 0.80 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL3120067 | 0.80 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL7526086 | 0.80 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1HPGDGRM5 | |
| SCHEMBL3120073 | 0.80 | KMT2A (0.59) | KMT2AMAPK1ALDH1A1HPGDGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1882689-B1 | TRI- OR TETRA-SUBSTITUTED-3-AMINOPYRROLIDINE DERIVATIVES | DAIICHI SANKYO CO LTD (JP) | 2013-07-10 | — | — | EP | disclosed |