⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15840377 | 1.00 | — | — | |
| SCHEMBL215360 | 1.00 | — | — | |
| SCHEMBL6314499 | 1.00 | — | — | |
| SCHEMBL17867090 | 1.00 | — | — | |
| SCHEMBL1114506 | 1.00 | — | — | |
| SCHEMBL6314501 | 1.00 | — | — | |
| SCHEMBL215359 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL738528 | 0.97 | DPP4 (0.47) | — | |
| Hydrochloric Acid SCHEMBL738527 | 0.97 | DPP4 (0.47) | — | |
| Hydrochloric Acid SCHEMBL6556151 | 0.97 | DPP4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240025949-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2024-01-25 | — | — | US | disclosed |
| US-20210324005-A1 | Beta-Arrestin Effectors and Compositions and Methods of Use Thereof | TREVENA, INC. | 2021-10-21 | — | — | US | disclosed |
| US-9534017-B2 | Beta-arrestin effectors and compositions and methods of use thereof | TREVENA, INC. (US) | 2017-01-03 | — | — | US | disclosed |
| US-20140357562-A1 | Beta-Arrestin Effectors And Compositions And Methods Of Use Thereof | TREVENA, INC. | 2014-12-04 | — | — | US | disclosed |
| US-8809260-B2 | β-arrestin effectors and compositions and methods of use thereof | TREVENA, INC. (US) | 2014-08-19 | — | — | US | disclosed |
| WO-2014095773-A1 | PEPTIDES AS OXYTOCIN AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2014-06-26 | — | — | WO | disclosed |
| US-20130274176-A1 | BETA-ARRESTIN EFFECTORS AND COMPOSITIONS AND METHODS OF USE THEREOF | TREVENA, INC. (US) | 2013-10-17 | — | — | US | disclosed |
| US-8486885-B2 | β-arrestin effectors and compositions and methods of use thereof | TREVENA, INC. (US) | 2013-07-16 | — | — | US | disclosed |