Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPER1 | Q99527 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12942704 | 0.94 | GPER1 (0.57) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL12722312 | 0.89 | GPER1 (0.53) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL916308 | 0.84 | GPER1 (0.60) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL15107072 | 0.83 | GPER1 (0.58) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL12722689 | 0.81 | GPER1 (0.60) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL12722304 | 0.80 | GPER1 (0.54) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL916068 | 0.79 | GPER1 (0.62) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL916305 | 0.79 | GPER1 (0.52) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL24203419 | 0.77 | NPC1 (0.61) | GPER1L3MBTL1GPR183NPC1RAB9A | |
| SCHEMBL5047258 | 0.77 | GPER1 (0.49) | GPER1L3MBTL1GPR183NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8487100-B2 | Compounds for binding to ER alpha/beta and GPR30, methods of treating disease states and conditions mediated through these receptors and identification thereof | STC.UNM (US) | 2013-07-16 | — | — | US | disclosed |