Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 20/20 | 0.61 |
| ▸ | ELOC | Q15369 | 12/20 | 0.61 |
| ▸ | ELOB | Q15370 | 12/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23431464 | 0.89 | VHL (0.58) | VHLELOCELOB | |
| SCHEMBL30566063 | 0.89 | VHL (0.62) | VHLELOCELOB | |
| SCHEMBL22525483 | 0.89 | VHL (0.62) | VHLELOCELOB | |
| SCHEMBL21458718 | 0.88 | VHL (0.65) | VHLELOCELOB | |
| SCHEMBL15112027 | 0.88 | VHL (0.65) | VHLELOCELOB | |
| SCHEMBL16276369 | 0.87 | VHL (0.60) | VHLELOCELOB | |
| SCHEMBL29874105 | 0.87 | VHL (0.60) | VHLELOCELOB | |
| SCHEMBL29336978 | 0.87 | VHL (0.60) | VHLELOCELOB | |
| SCHEMBL16267420 | 0.87 | VHL (0.60) | VHLELOCELOB | |
| SCHEMBL15110391 | 0.87 | VHL (0.60) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013106646-A2 | COMPOUNDS AND METHODS FOR THE INHIBITION OF VCB E3 UBIQUITIN LIGASE | YALE UNIVERSITY (US) | 2013-07-18 | — | — | WO | disclosed |