Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15112434 | 0.91 | MCHR1 (0.81) | MCHR1 | |
| SCHEMBL15111869 | 0.90 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL15111886 | 0.89 | MCHR1 (0.82) | MCHR1 | |
| SCHEMBL15111885 | 0.89 | MCHR1 (0.70) | MCHR1 | |
| SCHEMBL15112447 | 0.88 | MCHR1 (0.63) | MCHR1 | |
| SCHEMBL15112293 | 0.88 | MCHR1 (0.82) | MCHR1 | |
| SCHEMBL15112084 | 0.87 | MCHR1 (0.68) | MCHR1 | |
| SCHEMBL15111932 | 0.86 | MCHR1 (0.68) | MCHR1 | |
| SCHEMBL15111890 | 0.85 | MCHR1 (0.81) | MCHR1 | |
| SCHEMBL15112241 | 0.85 | MCHR1 (0.67) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9365540-B2 | Benzimidazole derivatives as MCH receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365540-B2 | Benzimidazole derivatives as MCH receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365540-B2 | Benzimidazole derivatives as MCH receptor antagonists | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-06-14 | — | — | US | disclosed |
| EP-2802571-A1 | BENZIMIDAZOLE DERIVATIVES AS MCH RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2014-11-19 | — | — | EP | disclosed |
| WO-2013105676-A1 | BENZIMIDAZOLE DERIVATIVES AS MCH RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-07-18 | — | — | WO | disclosed |