Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 19/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15111969 | 1.00 | VHL (0.59) | VHL | |
| SCHEMBL30856529 | 1.00 | VHL (0.59) | VHL | |
| SCHEMBL15110228 | 1.00 | VHL (0.59) | VHL | |
| SCHEMBL15126246 | 0.91 | VHL (0.58) | VHL | |
| SCHEMBL15126742 | 0.90 | VHL (0.57) | VHL | |
| SCHEMBL16266896 | 0.89 | VHL (0.56) | VHL | |
| SCHEMBL16266897 | 0.89 | VHL (0.56) | VHL | |
| SCHEMBL15110314 | 0.89 | VHL (0.56) | VHL | |
| SCHEMBL18089045 | 0.89 | VHL (0.70) | VHL | |
| SCHEMBL29547537 | 0.89 | VHL (0.70) | VHL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013106646-A2 | COMPOUNDS AND METHODS FOR THE INHIBITION OF VCB E3 UBIQUITIN LIGASE | YALE UNIVERSITY (US) | 2013-07-18 | — | — | WO | disclosed |