SCHEMBL15119354

SCHEMBL15119354

COC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.60
EPHX2 P34913 1/20 0.52
FABP5 Q01469 3/20 0.52
FABP7 O15540 2/20 0.51
CASP3 P42574 2/20 0.49
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
MDM4 O15151 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL44676 0.89 KMT2A (0.58) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL15058849 0.86 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL20903881 0.85 KMT2A (0.51) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL30433255 0.85 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL13981720 0.83 KMT2A (0.47) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL17167370 0.83 KMT2A (0.56) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL768971 0.83 KMT2A (0.52) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL13044481 0.83 KMT2A (0.52) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL28080728 0.82 KMT2A (0.47) KMT2AEPHX2FABP5FABP7CASP3
SCHEMBL29608029 0.82 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013105013-A1 MUTANT ANTIBODIES AND CONJUGATION THEREOF COVX TECHNOLOGIES IRELAND LIMITED (IE) 2013-07-18 WO disclosed