Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CALML3 | P27482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513435 | 1.00 | GRM2 (0.70) | GRM2SMN1; SMN2NPSR1GRM5POLB | |
| SCHEMBL6901412 | 0.92 | GRM2 (0.72) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL6901354 | 0.86 | GRM2 (0.75) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL6903582 | 0.85 | GRM2 (0.68) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1513873 | 0.85 | GRM2 (0.68) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1513473 | 0.85 | GRM2 (0.68) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1513651 | 0.85 | GRM2 (0.68) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1513476 | 0.85 | GRM2 (0.68) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1513610 | 0.85 | GRM2 (0.70) | GRM2SMN1; SMN2NPSR1POLBKMT2A | |
| SCHEMBL1513606 | 0.85 | GRM2 (0.70) | GRM2SMN1; SMN2NPSR1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | claimed |
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |