Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 9/20 | 0.74 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1513544 | 1.00 | GRM2 (0.74) | GRM2MAPTKDM4EMAPK1NPC1 | |
| SCHEMBL1513420 | 0.91 | GRM2 (0.79) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513417 | 0.91 | GRM2 (0.79) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513296 | 0.88 | GRM2 (0.75) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513300 | 0.88 | GRM2 (0.75) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513635 | 0.87 | GRM2 (0.73) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513639 | 0.87 | GRM2 (0.73) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL6902405 | 0.85 | GRM2 (0.82) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513462 | 0.85 | GRM2 (1.00) | GRM2MAPTKDM4EPOLBKMT2A | |
| SCHEMBL1513460 | 0.85 | GRM2 (1.00) | GRM2MAPTKDM4EPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |
| WO-2011034828-A1 | SUBSTITUTED PARA-BIPHENYLOXYMETHYL DIHYDRO OXAZOLOPYRIMIDINONES, PREPARATION AND USE THEREOF | SANOFI-AVENTIS (FR) | 2011-03-24 | — | — | WO | disclosed |