Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 20/20 | 0.69 |
| ▸ | GCKR | Q14397 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16509 | 0.82 | GCK (1.00) | GCKGCKR | |
| SCHEMBL17333 | 0.80 | GCK (1.00) | GCKGCKR | |
| SCHEMBL16319 | 0.76 | GCK (1.00) | GCKGCKR | |
| SCHEMBL16482 | 0.75 | GCK (0.75) | GCKGCKR | |
| SCHEMBL16882 | 0.73 | GCK (1.00) | GCKGCKR | |
| SCHEMBL18057 | 0.73 | GCK (0.69) | GCKGCKR | |
| SCHEMBL16938 | 0.72 | GCK (1.00) | GCKGCKR | |
| SCHEMBL15834 | 0.72 | GCK (1.00) | GCKGCKR | |
| SCHEMBL30956 | 0.72 | GCK (1.00) | GCKGCKR | |
| SCHEMBL16852 | 0.72 | GCK (0.73) | GCKGCKR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013123444-A1 | SULFONYL COMPOUNDS THAT INTERACT WITH GLUCOKINASE REGULATORY PROTEIN | AMGEN INC. (US) | 2013-08-22 | — | — | WO | disclosed |