Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK1 | P19367 | 1/20 | 0.35 |
| ▸ | HK2 | P52789 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.34 |
| ▸ | SLC5A2 | P31639 | 3/20 | 0.33 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.33 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.33 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.33 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14058429 | 0.95 | HK1 (0.35) | HK1HK2MAPK8SLC5A2LGALS9 | |
| SCHEMBL154836 | 0.95 | HK1 (0.35) | HK1HK2MAPK8SLC5A2LGALS9 | |
| SCHEMBL151971 | 0.95 | HK1 (0.35) | HK1HK2MAPK8SLC5A2LGALS9 | |
| SCHEMBL152934 | 0.93 | SMN1; SMN2 (0.39) | MAPK8SLC5A2ALDH1A1HTT | |
| SCHEMBL152105 | 0.90 | MEN1 (0.41) | SLC5A2ATM | |
| SCHEMBL27872824 | 0.90 | MEN1 (0.41) | SLC5A2ATM | |
| SCHEMBL152104 | 0.90 | MEN1 (0.41) | SLC5A2ATM | |
| SCHEMBL153287 | 0.85 | HK1 (0.37) | HK1HK2SLC5A2LGALS9LGALS1 | |
| SCHEMBL153497 | 0.85 | MAPK8 (0.41) | MAPK8SLC5A2 | |
| SCHEMBL154837 | 0.84 | MEN1 (0.41) | SLC5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| EP-2256103-A1 | Novel indicator platform | Biosynth AG (CH) | 2010-12-01 | — | — | EP | disclosed |