Glutathione

SCHEMBL15210325

CCN[C@@H](CCC(N)=O)C(=O)O.NC(CCC(=O)NC(CS)C(=O)NCC(=O)O)C(=O)O

nearest known ligand 0.73

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS1	P23219	1/20	0.73

▸	GSTK1	Q9Y2Q3	1/20	0.73

▸	GLO1	Q04760	2/20	0.56

▸	NOD1	Q9Y239	9/20	0.44

▸	ALOX15	P16050	1/20	0.40

▸	BLM	P54132	1/20	0.40

▸	PMP22	Q01453	1/20	0.40

▸	KMT2A	Q03164	1/20	0.40

▸	FOLH1	Q04609	2/20	0.39

▸	FNTA	P49354	2/20	0.38

▸	FNTB	P49356	2/20	0.38

▸	PGGT1B	P53609	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Glutathione SCHEMBL15210323	1.00	PTGS1 (0.73)	PTGS1GSTK1GLO1NOD1ALOX15
SCHEMBL29163790	0.95	PTGS1 (0.78)	PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL6465762	0.90	PTGS1 (0.90)	PTGS1GSTK1GLO1NOD1ALOX15
Glutathione SCHEMBL6465767	0.90	PTGS1 (0.90)	PTGS1GSTK1GLO1NOD1ALOX15
Glutathione SCHEMBL27657060	0.90	PTGS1 (0.90)	PTGS1GSTK1GLO1NOD1ALOX15
SCHEMBL28337837	0.89	PTGS1 (0.66)	PTGS1GSTK1GLO1NOD1ALOX15
SCHEMBL4657012	0.89	PTGS1 (0.66)	PTGS1GSTK1GLO1NOD1ALOX15
SCHEMBL2355650	0.87	PTGS1 (0.92)	PTGS1GSTK1GLO1NOD1FOLH1
SCHEMBL10324537	0.87	PTGS1 (0.92)	PTGS1GSTK1GLO1NOD1FOLH1
Glutathione SCHEMBL17629816	0.85	PTGS1 (0.90)	PTGS1GSTK1GLO1NOD1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013125675-A1	COMBINED ANTICANCER DRUG SENSITIVITY-DETERMINING MARKER	学校法人慶應義塾 (JP)	2013-08-29	—	—	WO	disclosed