Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.75 |
| ▸ | PPARA | Q07869 | 15/20 | 0.75 |
| ▸ | PPARG | P37231 | 8/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17444888 | 0.91 | PPARD (0.62) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL17431307 | 0.87 | PPARD (0.69) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL5859765 | 0.86 | PPARD (1.00) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL15211802 | 0.85 | PPARD (0.67) | PPARDPPARAPPARG | |
| SCHEMBL17431273 | 0.84 | PPARD (0.66) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL17431390 | 0.84 | PPARD (0.66) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL15211188 | 0.83 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL17431420 | 0.82 | PPARD (0.53) | PPARDPPARAPPARGFFAR1 | |
| SCHEMBL19191014 | 0.82 | PPARD (0.63) | PPARDPPARAPPARG | |
| SCHEMBL15211347 | 0.82 | PPARD (0.63) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-B1 | AROMATIC RING COMPOUND AS GHRELIN O-ACYLTRANSFERASE INHIBITOR | TAKEDA PHARMACEUTICALS CO (JP) | 2017-08-02 | — | — | EP | disclosed |
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |