Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.48 |
| ▸ | PPARA | Q07869 | 6/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 11/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431454 | 0.89 | PPARD (0.40) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL15211188 | 0.87 | PPARD (0.53) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL15211710 | 0.87 | PPARD (0.47) | PPARDPPARAFFAR1PPARGALDH1A1 | |
| SCHEMBL17431307 | 0.81 | PPARD (0.69) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL15211405 | 0.81 | PPARD (0.40) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431258 | 0.81 | PPARD (0.39) | PPARDPPARAFFAR1PPARGALDH1A1 | |
| SCHEMBL17431280 | 0.80 | PPARD (0.40) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL15211482 | 0.80 | PPARD (0.38) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL15211560 | 0.79 | PPARD (0.39) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17444869 | 0.79 | PPARD (0.57) | PPARDPPARAFFAR1PPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |