Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 16/20 | 0.46 |
| ▸ | PPARA | Q07869 | 14/20 | 0.46 |
| ▸ | PPARG | P37231 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17431478 | 0.88 | PPARA (0.41) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431486 | 0.87 | PPARD (0.46) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431332 | 0.83 | PPARA (0.42) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431488 | 0.83 | PPARA (0.44) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431303 | 0.83 | PPARD (0.62) | PPARDPPARAPPARGITGB3ITGB1 | |
| SCHEMBL17431420 | 0.82 | PPARD (0.53) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431456 | 0.82 | PPARD (0.52) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431357 | 0.82 | PPARA (0.41) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL17431474 | 0.81 | FFAR1 (0.41) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL15220561 | 0.81 | PPARD (0.51) | PPARDPPARAPPARGALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238639-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-01-19 | — | — | US | disclosed |
| EP-2838891-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2015-02-25 | — | — | EP | disclosed |
| WO-2013125732-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-08-29 | — | — | WO | disclosed |