Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CBLB | Q13191 | 1/20 | 0.39 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.33 |
| ▸ | PDE4A | P27815 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15786298 | 0.86 | POLB (0.48) | POLBTMPRSS4CYP1A2CYP2C9HPGD | |
| SCHEMBL16760606 | 0.85 | POLB (0.53) | POLBTMPRSS4CYP1A2CYP2C9HPGD | |
| SCHEMBL22231261 | 0.85 | POLB (0.47) | POLBTMPRSS4CYP1A2CYP2C9HPGD | |
| SCHEMBL31440661 | 0.84 | POLB (0.48) | POLBCBLBCYP1A2CYP2C9HPGD | |
| SCHEMBL22462323 | 0.84 | POLB (0.48) | POLBCBLBCYP1A2CYP2C9HPGD | |
| SCHEMBL15212582 | 0.82 | POLB (0.45) | POLBCBLBTMPRSS4CYP1A2CYP2C9 | |
| SCHEMBL17410605 | 0.81 | POLB (0.46) | POLBCBLBTMPRSS4CYP1A2CYP2C9 | |
| SCHEMBL22230816 | 0.81 | POLB (0.46) | POLBCBLBCYP1A2CYP2C9HPGD | |
| SCHEMBL19336127 | 0.80 | POLB (0.50) | POLBCBLBTMPRSS4CYP1A2CYP2C9 | |
| SCHEMBL30006828 | 0.80 | POLB (0.45) | POLBCYP1A2CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817296-B1 | HERBICIDALLY ACTIVE 3-(SULFIN-/SULFONIMIDOYL)-BENZAMIDES | BAYER IP GMBH (DE) | 2016-08-31 | — | — | EP | disclosed |
| US-9167819-B2 | Herbicidal 3-(sulfin-/sulfonimidoyl)-benzamides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| EP-2817296-A1 | HERBICIDAL 3 - ( SULFIN- /SULFONIMIDOYL) - BENZAMIDES | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124228-A1 | HERBICIDAL 3 - ( SULFIN- /SULFONIMIDOYL) - BENZAMIDES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |