Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.58 |
| ▸ | FGFR3 | P22607 | 12/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15217902 | 0.94 | FGFR1 (0.59) | FGFR1FGFR3 | |
| Hydrochloric Acid SCHEMBL15211653 | 0.93 | FGFR1 (0.58) | FGFR1FGFR3 | |
| SCHEMBL15211445 | 0.92 | FGFR1 (0.60) | FGFR1FGFR3 | |
| SCHEMBL15211542 | 0.92 | FGFR1 (0.61) | FGFR1FGFR3 | |
| SCHEMBL15217993 | 0.90 | FGFR1 (0.61) | FGFR1FGFR3 | |
| SCHEMBL16413956 | 0.89 | FGFR1 (0.59) | FGFR1FGFR3 | |
| SCHEMBL15217995 | 0.87 | FGFR1 (0.58) | FGFR1FGFR3 | |
| SCHEMBL15217990 | 0.87 | FGFR1 (0.58) | FGFR1FGFR3 | |
| SCHEMBL15217983 | 0.87 | FGFR1 (0.71) | FGFR1FGFR3 | |
| SCHEMBL15217895 | 0.86 | FGFR1 (0.57) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2817311-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | Bayer Intellectual Property GmbH (DE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124316-A1 | SUBSTITUTED BENZOTHIENYL-PYRROLOTRIAZINES AND USES THEREOF | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-08-29 | — | — | WO | disclosed |