SCHEMBL15213150

SCHEMBL15213150

N#CC1(Cc2cc(COc3cc(C(CC(=O)O)C4CC4)c(F)cn3)cnc2-c2cc(ON)ccc2F)CCCC1

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.44
FFAR4 Q5NUL3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16318924 0.93 FFAR1 (0.52) FFAR1FFAR4
SCHEMBL16319329 0.86 FFAR1 (0.44) FFAR1
SCHEMBL16318997 0.69 FFAR1 (0.65) FFAR1
SCHEMBL16319322 0.69 FFAR1 (0.36) FFAR1
SCHEMBL15213180 0.69 FFAR1 (0.65) FFAR1
SCHEMBL15213184 0.68 FFAR1 (0.65) FFAR1
SCHEMBL16319117 0.67 CNR1 (0.35) FFAR1
SCHEMBL16318765 0.67 FFAR1 (0.63) FFAR1FFAR4
SCHEMBL16319057 0.67 FFAR1 (0.57) FFAR1FFAR4
SCHEMBL16318884 0.66 FFAR1 (0.35) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013122029-A1 AROMATIC RING COMPOUND 武田薬品工業株式会社 (JP) 2013-08-22 WO disclosed