Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.70 |
| ▸ | MAOB | P27338 | 3/20 | 0.61 |
| ▸ | MAOA | P21397 | 2/20 | 0.61 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.46 |
| ▸ | RELA | Q04206 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1570323 | 1.00 | KDM1A (0.70) | KDM1AMAOBMAOACNR1TLR2 | |
| SCHEMBL31728997 | 1.00 | KDM1A (0.70) | KDM1AMAOBMAOACNR1TLR2 | |
| SCHEMBL15235894 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL16019177 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL13453249 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL17718439 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL15096181 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL15099831 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL17718446 | 0.87 | KDM1A (0.71) | KDM1AMAOBMAOATLR2TLR1 | |
| SCHEMBL17287389 | 0.86 | KDM1A (0.70) | KDM1AMAOBMAOATLR2TLR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013120940-A2 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2013-08-22 | — | — | WO | disclosed |